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Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment

Environmental enrichment produces protective addiction and depression phenotypes in rats. ΔFosB is a transcription factor that regulates reward in the brain and is induced by psychological stress as well as drugs of abuse. However, the role played by ΔFosB in the protective phenotypes of environment...

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Autors principals: Zhang, Yafang, Crofton, Elizabeth J., Li, Dingge, Lobo, Mary Kay, Fan, Xiuzhen, Nestler, Eric J., Green, Thomas A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148937/
https://ncbi.nlm.nih.gov/pubmed/25221490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00297
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