Expanding the Proteome of an RNA Virus by Phosphorylation of an Intrinsically Disordered Viral Protein

The human proteome contains myriad intrinsically disordered proteins. Within intrinsically disordered proteins, polyproline-II motifs are often located near sites of phosphorylation. We have used an unconventional experimental paradigm to discover that phosphorylation by protein kinase A (PKA) occur...

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Autori principali: Cordek, Daniel G., Croom-Perez, Tayler J., Hwang, Jungwook, Hargittai, Michele R. S., Subba-Reddy, Chennareddy V., Han, Qingxia, Lodeiro, Maria Fernanda, Ning, Gang, McCrory, Thomas S., Arnold, Jamie J., Koc, Hasan, Lindenbach, Brett D., Showalter, Scott A., Cameron, Craig E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148867/
https://ncbi.nlm.nih.gov/pubmed/25031324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589911
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