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AAA Peroxins and Their Recruiter Pex26p Modulate the Interactions of Peroxins Involved in Peroxisomal Protein Import

Pex1p and Pex6p are required for the relocation of the import receptor Pex5p from the peroxisomal membrane to the cytosol. We herein show that mammalian Pex26p directly binds to Pex14p, the initial docking receptor of Pex5p, and interacts with Pex5p via Pex14p. The binding affinity of Pex26p to Pex1...

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Detalles Bibliográficos
Main Authors: Tamura, Shigehiko, Matsumoto, Naomi, Takeba, Ryota, Fujiki, Yukio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148862/
https://ncbi.nlm.nih.gov/pubmed/25016021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588038
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