Sp6 and Sp8 Transcription Factors Control AER Formation and Dorsal-Ventral Patterning in Limb Development

The formation and maintenance of the apical ectodermal ridge (AER) is critical for the outgrowth and patterning of the vertebrate limb. The induction of the AER is a complex process that relies on integrated interactions among the Fgf, Wnt, and Bmp signaling pathways that operate within the ectoderm...

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Bibliographic Details
Main Authors: Haro, Endika, Delgado, Irene, Junco, Marisa, Yamada, Yoshihiko, Mansouri, Ahmed, Oberg, Kerby C., Ros, Marian A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148220/
https://ncbi.nlm.nih.gov/pubmed/25166858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004468
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