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Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals

Involvement of cancer stem cells (CSC) in initiation, progression, relapse, and therapy-resistance of colorectal cancer (CRC) warrants search for small molecules as ‘adjunct-therapy’ to target both colon CSC and bulk tumor population. Herein, we assessed the potential of silibinin to eradicate colon...

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Autori principali: Kumar, Sushil, Raina, Komal, Agarwal, Chapla, Agarwal, Rajesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148115/
https://ncbi.nlm.nih.gov/pubmed/24970802
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