Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells

Endoplasmic reticulum stress from unfolded proteins is associated with the proliferation of pancreatic tumor cells, making the many regulatory molecules of this pathway appealing targets for therapy. The objective of our study was to assess potential therapeutic efficacy of inhibitors of unfolded pr...

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Detalhes bibliográficos
Main Authors: Chien, Wenwen, Ding, Ling-Wen, Sun, Qiao-Yang, Torres-Fernandez, Lucia A, Tan, Siew Zhuan, Xiao, Jinfen, Lim, Su Lin, Garg, Manoj, Lee, Kian Leong, Kitajima, Shojiro, Takao, Sumiko, Leong, Wei Zhong, Sun, Haibo, Tokatly, Itay, Poellinger, Lorenz, Gery, Sigal, Koeffler, Phillip H
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148107/
https://ncbi.nlm.nih.gov/pubmed/24952679
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