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PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition

Summary: Prions are self-templating protein aggregates that stably perpetuate distinct biological states and are of keen interest to researchers in both evolutionary and biomedical science. The best understood prions are from yeast and have a prion-forming domain with strongly biased amino acid comp...

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Autori principali: Lancaster, Alex K., Nutter-Upham, Andrew, Lindquist, Susan, King, Oliver D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147883/
https://ncbi.nlm.nih.gov/pubmed/24825614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu310
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