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Alternative splicing and retinal degeneration
Alternative splicing is highly regulated in tissue-specific and development-specific patterns, and it has been estimated that 15% of disease-causing point mutations affect pre-mRNA splicing. In this review, we consider the cis-acting splice site and trans-acting splicing factor mutations that affect...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4147722/ https://ncbi.nlm.nih.gov/pubmed/23647439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cge.12181 |
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