Divergence of Primary Cognate B- and T-Cell Proliferative Responses to Subcutaneous and Intravenous Immunization with Virus-Like Particles

A major advantage of virus-like particle (VLP) vaccines against HIV is their structural identity to wild-type viruses, ensuring that antigen-specific B-cells encounter the envelope protein in its natural conformation. For the induction of affinity-matured antibodies, the B-cells must also obtain hel...

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Hlavní autoři: Temchura, Vladimir, Kalinin, Svetlana, Nabi, Ghulam, Tippler, Bettina, Niezold, Thomas, Überla, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147698/
https://ncbi.nlm.nih.gov/pubmed/25153345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6083334
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