Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and In Silico Analysis

Although recent data suggest aristolochic acid as a putative cause of Balkan endemic nephropathy (BEN), evidence also exists in favor of ochratoxin A (OTA) exposure as risk factor for the disease. The potential role of xenobiotic metabolizing enzymes, such as the glutathione transferases (GSTs), in...

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Autors principals: Reljic, Zorica, Zlatovic, Mario, Savic-Radojevic, Ana, Pekmezovic, Tatjana, Djukanovic, Ljubica, Matic, Marija, Pljesa-Ercegovac, Marija, Mimic-Oka, Jasmina, Opsenica, Dejan, Simic, Tatjana
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147586/
https://ncbi.nlm.nih.gov/pubmed/25111321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6082348
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