Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.
The scl gene encodes a basic-helix-loop-helix transcription factor which was identified through its involvement in chromosomal translocations in T-cell leukemia. To elucidate its physiological role, scl was targeted in embryonic stem cells. Mice heterozygous for the scl null mutation were intercross...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1995
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.7075 |
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