Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström's Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome

We performed IGH clonotypic sequence analysis in WM in order to determine whether a preferential IGH gene rearrangement was observed and to assess IGHV mutational status in blood and/or bone marrow samples from 36 WM patients. In addition we investigated the presence of MYD88 L265P somatic mutation....

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Main Authors: Petrikkos, Loizos, Kyrtsonis, Marie-Christine, Roumelioti, Maria, Georgiou, George, Efthymiou, Anna, Tzenou, Tatiana, Panayiotidis, Panayiotis
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147361/
https://ncbi.nlm.nih.gov/pubmed/25197661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/809103
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