Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1

Expression of IGFBP2 (Insulin-like Growth Factor Binding Protein 2) has been positively correlated with glioma progression. Although the proteolysis of IGFBP2 has been widely recognized, with consequences as a major modulator of IGFII signaling, the relevance of this post-translational modification...

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Detalhes bibliográficos
Main Authors: Martino-Echarri, Estefanía, Fernández-Rodríguez, Rubén, Bech-Serra, Joan Josep, Plaza-Calonge, María del Carmen, Vidal, Noemi, Casal, Carmen, Colomé, Nuria, Seoane, Joan, Canals, Francesc, Rodríguez-Manzaneque, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147324/
https://ncbi.nlm.nih.gov/pubmed/24962328
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