Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis

Although novel drugs have contributed immensely to improving outcomes of patients with multiple myeloma (MM), many patients develop drug resistance and ultimately succumb to MM. Here, we show that artesunate, an anti-malarial drug, reliably induces cell death in vitro in naïve as well as drug-resist...

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Détails bibliographiques
Auteurs principaux: Papanikolaou, Xenofon, Johnson, Sarah, Garg, Tarun, Tian, Erming, Tytarenko, Ruslana, Zhang, Qing, Stein, Caleb, Barlogie, Bart, Epstein, Joshua, Heuck, Christoph
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147310/
https://ncbi.nlm.nih.gov/pubmed/24948357
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