Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors

Although imatinib mesylate (IM) has revolutionized the management of gastrointestinal stromal tumors (GISTs), drug resistance remains a challenge. Previous studies have shown that the expression of aurora kinase A (AURKA) predicts recurrence in patients with primary, surgically resected GISTs. The c...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yeh, Chun-Nan, Yen, Chueh-Chuan, Chen, Yen-Yang, Cheng, Chi-Tung, Huang, Shih-Chiang, Chang, Ting-Wei, Yao, Fang-Yi, Lin, Yung-Chan, Wen, Yao-Shan, Chiang, Kun-Chun, Chen, Jen-Shi, Yeh, Ta-Sen, Tzeng, Cheng-Hwai, Chao, Ta-Chung, Fletcher, Jonathan A.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147307/
https://ncbi.nlm.nih.gov/pubmed/24901229
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