Evidence that the 50-kDa substrate of brefeldin A-dependent ADP-ribosylation binds GTP and is modulated by the G-protein beta gamma subunit complex.

Brefeldin A, a fungal metabolite that inhibits membrane transport, induces the mono(ADP-ribosyl)ation of two cytosolic proteins of 38 and 50 kDa as judged by SDS/PAGE. The 38-kDa substrate has been previously identified as glyceraldehyde-3-phosphate dehydrogenase (GAPDH). We report that the 50-kDa B...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Di Girolamo, M, Silletta, M G, De Matteis, M A, Braca, A, Colanzi, A, Pawlak, D, Rasenick, M M, Luini, A, Corda, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.7065
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