Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells

AIM: To investigate the combined chemotherapeutic effects of celecoxib when used with 5-FU in vitro. METHODS: Two human colon cancer cell lines (HCT-15 and HT-29) were treated with 5-FU and celecoxib, alone and in combination. The effects of each drug were evaluated using the MTT [3- (4, 5-dimethylt...

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Bibliographic Details
Main Authors: Lim, Yun Jeong, Rhee, Jong Chul, Bae, Young Mee, Chun, Wan Joo
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Co., Limited 2007
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146971/
https://ncbi.nlm.nih.gov/pubmed/17461495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i13.1947
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