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Genetic diversity of the hepatitis C virus: Impact and issues in the antiviral therapy

The hepatitis C Virus (HCV) presents a high degree of genetic variability which is explained by the combination of a lack of proof reading by the RNA dependant RNA polymerase and a high level of viral replication. The resulting genetic polymorphism defines a classification in clades, genotypes, subt...

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Detalhes bibliográficos
Main Authors: Le Guillou-Guillemette, H, Vallet, S, Gaudy-Graffin, C, Payan, C, Pivert, A, Goudeau, A, Lunel-Fabiani, F
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146759/
https://ncbi.nlm.nih.gov/pubmed/17552024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i17.2416
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