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Beyond Genotype: Serotonin Transporter Epigenetic Modification Predicts Human Brain Function

We examined epigenetic regulation in regards to behaviorally and clinically relevant human brain function. Specifically, we found that increased promoter methylation of the serotonin transporter gene predicted increased threat-related amygdala reactivity and decreased mRNA expression in postmortem a...

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Detalhes bibliográficos
Main Authors: Nikolova, Yuliya S., Koenen, Karestan C., Galea, Sandro, Wang, Chiou-Miin, Seney, Marianne L., Sibille, Etienne, Williamson, Douglas E., Hariri, Ahmad R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146649/
https://ncbi.nlm.nih.gov/pubmed/25086606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3778
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