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Effects of Lubiprostone on Pacemaker Activity of Interstitial Cells of Cajal from the Mouse Colon

Lubiprostone is a chloride (Cl(-)) channel activator derived from prostaglandin E(1) and used for managing constipation. In addition, lubiprostone affects the activity of gastrointestinal smooth muscles. Interstitial cells of Cajal (ICCs) are pacemaker cells that generate slow-wave activity in smoot...

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Detalhes bibliográficos
Main Authors: Jiao, Han-Yi, Kim, Dong Hyun, Ki, Jung Suk, Ryu, Kwon Ho, Choi, Seok, Jun, Jae Yeoul
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146637/
https://ncbi.nlm.nih.gov/pubmed/25177167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2014.18.4.341
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