Non-Classical ProIL-1beta Activation during Mammary Gland Infection Is Pathogen-Dependent but Caspase-1 Independent

Infection of the mammary gland with live bacteria elicits a pathogen-specific host inflammatory response. To study these host-pathogen interactions wild type mice, NF-kappaB reporter mice as well as caspase-1 and IL-1beta knockout mice were intramammarily challenged with Escherichia coli (E. coli) a...

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Autori principali: Breyne, Koen, Cool, Steven K., Demon, Dieter, Demeyere, Kristel, Vandenberghe, Tom, Vandenabeele, Peter, Carlsen, Harald, Van Den Broeck, Wim, Sanders, Niek N., Meyer, Evelyne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146512/
https://ncbi.nlm.nih.gov/pubmed/25162221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105680
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