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Charged Residues Distribution Modulates Selectivity of the Open State of Human Isoforms of the Voltage Dependent Anion-Selective Channel

Voltage Dependent Anion-selective Channels (VDACs) are pore-forming proteins located in the outer mitochondrial membrane. They are responsible for the access of ions and energetic metabolites into the inner membrane transport systems. Three VDAC isoforms exist in mammalian, but their specific role i...

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Detalhes bibliográficos
Main Authors: Amodeo, Giuseppe Federico, Scorciapino, Mariano Andrea, Messina, Angela, De Pinto, Vito, Ceccarelli, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146382/
https://ncbi.nlm.nih.gov/pubmed/25084457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103879
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