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Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle

Dystrophin is a large, submembrane cytoskeletal protein, absence of which causes Duchenne muscular dystrophy. Utrophin is a dystrophin homologue found in both muscle and brain whose physiological function is unknown. Recordings of single-channel activity were made from membrane patches on skeletal m...

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Autori principali: Tan, Nhi, Lansman, Jeffry B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146377/
https://ncbi.nlm.nih.gov/pubmed/24879867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.274332
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