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Protective effect of alpha-synuclein knockdown on methamphetamine-induced neurotoxicity in dopaminergic neurons

The over-expression of α-synuclein is a major factor in the death of dopaminergic neurons in a methamphetamine-induced model of Parkinson's disease. In the present study, α-synuclein knockdown rats were created by injecting α-synuclein-shRNA lentivirus stereotaxically into the right striatum of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tai, Yunchun, Chen, Ling, Huang, Enping, Liu, Chao, Yang, Xingyi, Qiu, Pingming, Wang, Huijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146216/
https://ncbi.nlm.nih.gov/pubmed/25206917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.133146
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