A novel transgenic mouse model of Chinese Charcot-Marie-Tooth disease type 2L

We previously found that the K141N mutation in heat shock protein B8 (HSPB8) was responsible for Charcot-Marie-Tooth disease type 2L in a large Chinese family. The objective of the present study was to generate a transgenic mouse model bearing the K141N mutation in the human HSPB8 gene, and to deter...

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Detalhes bibliográficos
Main Authors: Zhang, Ruxu, Zhang, Fufeng, Li, Xiaobo, Huang, Shunxiang, Zi, Xiaohong, Liu, Ting, Liu, Sanmei, Li, Xuning, Xia, Kun, Pan, Qian, Tang, Beisha
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
Assuntos:
Research and Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146190/
https://ncbi.nlm.nih.gov/pubmed/25206829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.128248
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