Autophagy and neurodegenerative disorders

Accumulation of aberrant proteins and inclusion bodies are hallmarks in most neurodegenerative diseases. Consequently, these aggregates within neurons lead to toxic effects, overproduction of reactive oxygen species and oxidative stress. Autophagy is a significant intracellular mechanism that remove...

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Bibliographic Details
Main Authors: Kesidou, Evangelia, Lagoudaki, Roza, Touloumi, Olga, Poulatsidou, Kyriaki-Nefeli, Simeonidou, Constantina
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2013
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146038/
https://ncbi.nlm.nih.gov/pubmed/25206537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.007
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