Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer's disease-like rats

A correlation between metabolic alterations of neuroactive steroids and Alzheimer's disease remains unknown. In the present study, amyloid beta (Aβ) 25–35 (Aβ(25–35)) injected into the bilateral hippocampus CA1 region significantly reduced learning and memory. At the biochemical level, hippocam...

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Detalhes bibliográficos
Main Authors: Liu, Sha, Wu, Honghai, Xue, Gai, Ma, Xin, Wu, Jie, Qin, Yabin, Hou, Yanning
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2013
Assuntos:
Research and Report Article: Neurodegenerative Disease and Neural Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146013/
https://ncbi.nlm.nih.gov/pubmed/25206601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.30.002
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