Neurotoxic effects of iron overload under high glucose concentration

Iron overload can lead to cytotoxicity, and it is a risk factor for diabetic peripheral neuropathy. However, the underlying mechanism remains unclear. We conjectured that iron overload-induced neurotoxicity might be associated with oxidative stress and the NF-E2-related factor 2 (Nrf2)/ARE signaling...

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Detalhes bibliográficos
Main Authors: Zhao, Shi, Zhang, Lin, Xu, Zihui, Chen, Weiqun
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2013
Assuntos:
Research and Report Article: Peripheral Nerve Injury and Neural Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146010/
https://ncbi.nlm.nih.gov/pubmed/25206665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.36.008
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