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Calcium-dependent proteasome activation is required for axonal neurofilament degradation

Even though many studies have identified roles of proteasomes in axonal degeneration, the molecular mechanisms by which axonal injury regulates proteasome activity are still unclear. In the present study, we found evidence indicating that extracellular calcium influx is an upstream regulator of prot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Joo Youn, Jang, So Young, Shin, Yoon Kyung, Suh, Duk Joon, Park, Hwan Tae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146008/
https://ncbi.nlm.nih.gov/pubmed/25206662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.36.005
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