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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

The 'gold standard' for oncogenic HPV detection is the demonstration of transcriptionally active high-risk HPV in tumor tissue. However, detection of E6/E7 mRNA by quantitative reverse transcription polymerase chain reaction (qRT-PCR) requires RNA extraction which destroys the tumor tissue...

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Dettagli Bibliografici
Autori principali: Wang, Hongwei, Wang, Mindy Xiao-Ming, Su, Nan, Wang, Li-chong, Wu, Xingyong, Bui, Son, Nielsen, Allissa, Vo, Hong-Thuy, Nguyen, Nina, Luo, Yuling, Ma, Xiao-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145807/
https://ncbi.nlm.nih.gov/pubmed/24637627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51426
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