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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers.

c-Src is a nontransforming tyrosine kinase that participates in signaling events mediated by a variety of polypeptide growth factor receptors, including the epidermal growth factor receptor (EGFR). Overexpression and continual ligand stimulation of the EGFR results in morphological transformation of...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Maa, M C, Leu, T H, McCarley, D J, Schatzman, R C, Parsons, S J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7542783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.6981
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