2-(Trimethylammonium) Ethyl (R)-3-Methoxy-3-oxo-2-Stearamidopropyl Phosphate Suppresses Osteoclast Maturation and Bone Resorption by Targeting Macrophage-Colony Stimulating Factor Signaling

2-(Trimethylammonium) ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate [(R)-TEMOSPho], a derivative of an organic chemical identified from a natural product library, promotes highly efficient megakaryopoiesis. Here, we show that (R)-TEMOSPho blocks osteoclast maturation from progenitor cells o...

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Autors principals: Park, So Jeong, Park, Doo Ri, Bhattarai, Deepak, Lee, Kyeong, Kim, Jaesang, Bae, Yun Soo, Lee, Soo Young
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145375/
https://ncbi.nlm.nih.gov/pubmed/25139265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.0190
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