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Critical limitations of consensus clustering in class discovery

Consensus clustering (CC) has been adopted for unsupervised class discovery in many genomic studies. It calculates how frequently two samples are grouped together in repeated clustering runs, and uses the resulting pairwise "consensus rates" for visual demonstration that clusters exist, fo...

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Bibliographic Details
Main Authors: Șenbabaoğlu, Yasin, Michailidis, George, Li, Jun Z.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145288/
https://ncbi.nlm.nih.gov/pubmed/25158761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06207
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