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Persistent pharmacokinetic challenges to pediatric drug development

The development of new therapeutic agents for the mitigation of pediatric disorders is largely hindered by the inability for investigators to assess pediatric pharmacokinetics (PK) in healthy patients due to substantial safety concerns. Pediatric patients are a clinical moving target for drug delive...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sage, Daniel P., Kulczar, Christopher, Roth, Wyatt, Liu, Wanqing, Knipp, Gregory T.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145254/
https://ncbi.nlm.nih.gov/pubmed/25221567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00281
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