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Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cells
L-asparaginase (L-ASP) is a therapeutic enzyme used clinically for the treatment of childhood acute lymphoblastic leukemia. L-ASP’s anticancer activity is believed to be associated primarily with depletion of asparagine, but secondary glutaminase activity has also been implicated in its anticancer m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4145215/ https://ncbi.nlm.nih.gov/pubmed/25177232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-014-0634-1 |
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