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Abnormal High-Frequency Burst Firing of Cerebellar Neurons in Rapid-Onset Dystonia-Parkinsonism

Loss-of-function mutations in the α3 isoform of the Na(+)/K(+) ATPase (sodium pump) are responsible for rapid-onset dystonia parkinsonism (DYT12). Recently, a pharmacological model of DYT12 was generated implicating both the cerebellum and basal ganglia in the disorder. Notably, partially blocking s...

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Bibliografiska uppgifter
Huvudupphovsmän: Fremont, Rachel, Calderon, D. Paola, Maleki, Sara, Khodakhah, Kamran
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145175/
https://ncbi.nlm.nih.gov/pubmed/25164667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1409-14.2014
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