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Covalently tethered TGF-β1 with encapsulated chondrocytes in a PEG hydrogel system enhances extracellular matrix production

Healing articular cartilage defects remains a significant clinical challenge because of its limited capacity for self-repair. While delivery of autologous chondrocytes to cartilage defects has received growing interest, combining cell-based therapies with growth factor delivery that can locally sign...

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Bibliographic Details
Main Authors: Sridhar, Balaji V., Doyle, Nicholas R., Randolph, Mark A., Anseth, Kristi S.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145048/
https://ncbi.nlm.nih.gov/pubmed/24616326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35115
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