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Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.

The gene product of the recently cloned mouse obese gene (ob) is important in regulating adipose tissue mass. ob RNA is expressed specifically by mouse adipocytes in vivo in each of several different fat cell depots, including brown fat. ob RNA is also expressed in cultured 3T3-442A preadipocyte cel...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Maffei, M, Fei, H, Lee, G H, Dani, C, Leroy, P, Zhang, Y, Proenca, R, Negrel, R, Ailhaud, G, Friedman, J M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.6957
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