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CLINICAL TRIAL EVIDENCE SUPPORTING FDA APPROVAL OF NOVEL THERAPEUTICS, 2005–2012

IMPORTANCE: Many patients and physicians assume that the safety and effectiveness of newly approved therapeutics is well understood; however, the strength of the clinical trial evidence supporting approval decisions by the Food and Drug Administration (FDA) has not been evaluated. OBJECTIVES: To cha...

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Detalhes bibliográficos
Main Authors: Downing, Nicholas S., Aminawung, Jenerius A., Shah, Nilay D., Krumholz, Harlan M., Ross, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144867/
https://ncbi.nlm.nih.gov/pubmed/24449315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2013.282034
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