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Enantioselective Synthesis of Polycyclic Nitrogen Heterocycles by Rh-Catalyzed Alkene Hydroacylation: Constructing Six-Membered Rings in the Absence of Chelation Assistance

[Image: see text] Catalytic, enantioselective hydroacylations of N-allylindole-2-carboxaldehydes and N-allylpyrrole-2-carboxaldehydes are reported. In contrast to many alkene hydroacylations that form six-membered rings, these annulative processes occur in the absence of ancillary functionality to s...

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Main Authors: Du, Xiang-Wei, Ghosh, Avipsa, Stanley, Levi M.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144754/
https://ncbi.nlm.nih.gov/pubmed/25020184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol501869s
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