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Immunization of mice against coccidioidomycosis with a subcellular vaccine.

In vitro-cultivated spherules of Coccidioides immitis were disrupted in a Braun homogenizer. The resultant wall fragments were separated from cell sap and endospores by centrifugation. Extraction of the walls with phosphate-buffered saline yielded a subcellular fraction that was immunogenic in mice....

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Detalhes bibliográficos
Main Authors: Pappagianis, D, Hector, R, Levine, H B, Collins, M S
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC414469/
https://ncbi.nlm.nih.gov/pubmed/478645
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