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RAPID IDH1 GENE MUTATION ANALYSIS FOR INTRAOPERATIVE PATHOLOGICAL DIAGNOSIS

BACKGROUND: (blind field). METHODS: DNA extracted in 15 min from glioma tissue collected during surgery was used to test for R132 point mutations of the IDH1 gene by using real-time PCR/high resolution melting analysis method (LightCycler 480 system). Normally, detecting IDH1 mutations requires abou...

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Bibliographische Detailangaben
Hauptverfasser: Adachi, Jun-ichi, Mishima, Kazuhiko, Suzuki, Tomonari, Fujimaki, Takamitsu, Nishikawa, Ryo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144635/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.21
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