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BENEFICIAL OUTCOMES AFTER PCV PLUS RT IN OLIGODENDROGLIAL TUMORS ARE ASSOCIATED WITH DETECTION OR RISK OF AN IDH MUTATION

BACKGROUND: Oligodendroglial tumors harbor IDH mutations and risk of this type of cancer is associated with a germ-line polymorphism at 8q. In addition, when these tumors harbor a co-deletion of 1p19q, they can be highly chemo-sensitive. Indeed, patients with anaplastic tumors (i.e., AO/AOA) with 1p...

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Detalhes bibliográficos
Main Authors: Cairncross, Gregory, Wang, Meihua, Jenkins, Robert, Shaw, Edward, Giannini, Caterina, Brachman, David, Buckner, Jan, Fink, Karen, Souhami, Luis, Laperriere, Normand, Huse, Jason T., Mehta, Minesh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144624/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.11
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