DIRECT CELL CONTACT BETWEEN BRAIN ENDOTHELIAL CELLS AND GLIOMA STEM CELLS PROMOTES ENDOTHELIAL CELL MIGRATION

BACKGROUND: A histologic characteristic of glioblastoma tumors (GBM) is angiogenesis, which requires endothelial cell (EC) sprouting and migration. This is thought to be facilitated by signals in a specialized microenvironment, the perivascular niche, where glioma stem cells (GSC) reside in proximit...

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Main Authors: Gladson, Candece L., Burgett, Monica E., Lathia, Justin D., Roth, Patrick, Huang, Ping, Vasanji, Amit, Li, Meizhang, Bao, Shideng, Nowacki, Amy, RIch, Jeremy N., Weller, Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144596/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.49
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