METASTASIS AND TUMOR RECURRENCE FROM RARE SOX9-POSITIVE CELLS IN MYCN-DRIVEN MEDULLOBLASTOMA

BACKGROUND: Tumor recurrence is the main cause of death for children with medulloblastoma, the most common malignant childhood brain tumor. The MYCN oncogene is a poor prognosis marker and is amplified in the molecularly defined SHH and Group 4 subgroups but rarely in WNT and Group 3 subgroups of hu...

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Autors principals: Swartling, Fredrik J., Savov, Vasil, Čančer, Matko, Bolin, Sara, Fotaki, Grammatiki, Dubuc, Adrian, Remke, Marc, Ramaswamy, Vijay, Weishaupt, Holger, Taylor, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144565/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.20
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