IMMUNE CHECKPOINT BLOCKADE FOR GLIOBLASTOMA: PRECLINICAL ACTIVITY OF SINGLE AGENT AND COMBINATORIAL THERAPY

BACKGROUND: Outcome for glioblastoma (GBM) remains dismal and innovative treatment strategies are desperately needed. Growing data support the contribution of local and systemic immune checkpoint molecules to regulating immunosuppression by GBM tumors. METHODS: Luciferized GL261 cells (GL261-Luc) we...

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Main Authors: Reardon, David A., Gokhale, Praful, Ligon, Keith, Liao, Xiaoyun, Rodig, Scott, Zhou, Jun, Win, Lei, Hodi, Frank S., Kohl, Nancy E., Freeman, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144507/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.40
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