TELOMERE LENGTH VARIANTS ARE ASSOCIATED WITH HIGH-GRADE GLIOMA RISK: IDENTIFICATION OF A NOVEL GLIOMA RISK LOCUS BY GENOME-WIDE ASSOCIATION STUDY

BACKGROUND: Glioblastoma, the most common and aggressive form of glioma, has a median survival time of just 15 months. Both inherited and acquired genetic variation influence gliomagenesis. Previous genome-wide association studies (GWAS) have discovered seven glioma risk loci, including two in genes...

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Main Authors: Walsh, Kyle M., Codd, Veryan, Smirnov, Ivan V., Rice, Terri, Decker, Paul A., Hansen, Helen M., Kollmeyer, Thomas, Kosel, Matthew L., Molinaro, Annette M., McCoy, Lucie S., Bracci, Paige M., Cabriga, Belinda S., Pekmezci, Melike, Zheng, Shichun, Wiemels, Joseph L., Pico, Alexander R., Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael D., Lachance, Daniel H., O'Neill, Brian P., Sicotte, Hugues, Eckel-Passow, Jeanette E., van der Harst, Pim, Wiencke, John K., Samani, Nilesh J., Jenkins, Robert B., Wrensch, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144506/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.4
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