FREQUENT H3F3A K27M MUTATIONS IN THALAMIC GLIOMAS FROM YOUNG ADULT PATIENTS

BACKGROUND: Mutations in the H3F3A gene, which encodes histone H3.3, were recently reported in cases of pediatric glioblastoma. H3F3A K27M mutations occur in gliomas that arise at midline locations, including the pons, thalamus, and spine; moreover, this particular mutation is found mainly in tumors...

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Autors principals: Mukasa, Akitake, Aihara, Koki, Gotoh, Kengo, Saito, Kuniaki, Nagae, Genta, Tsuji, Shingo, Tatuno, Kenji, Yamamoto, Shogo, Takayanagi, Shunsaku, Narita, Yoshitaka, Shibui, Soichiro, Aburatani, Hiroyuki, Saito, Nobuhito
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144499/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.33
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