MUTATION-BASED MOLECULAR GLIOMA CLASSIFICATION: PREVALENCE AND ASSOCIATION WITH GERMLINE RISK SNPS

BACKGROUND: Specific germline alterations within TERT, EGFR, CCDC26, CDKN2A/B, PHLDB1, TP53 and RTEL1 are associated with development of glioma. While germline variants in TERT are associated with all gliomas, others are associated with specific morphologic and/or molecular subtypes. For example, th...

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Main Authors: Jenkins, Robert Brian, Decker, Paul, Kosel, Matt, Eckel-Passow, Jeanette, Walsh, Kyle M., Smirnov, Ivan V., Caron, Alissa, Kollmeyer, Tom, Rice, Terri, Hansen, Helen M., Molinaro, Annette M., McCoy, Lucie S., Bracci, Paige M., Cabriga, Belinda S., Marshall, Roxanne, Pekmezci, Melike, Zheng, Shichun, O'Neill, Brian, Buckner, Jan, Giannini, Caterina, Perry, Arie, Tihan, Tarik, Berger, Mitchell S., Chang, Susan M., Prados, Michael, Wiemels, Jospeh, Wiencke, John, Wrensch, Margaret, Lachance, Dan
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144495/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.3
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