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Using Mendelian inheritance errors as quality control criteria in whole genome sequencing data set

Although the technical and analytic complexity of whole genome sequencing is generally appreciated, best practices for data cleaning and quality control have not been defined. Family based data can be used to guide the standardization of specific quality control metrics in nonfamily based data. Give...

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Detalhes bibliográficos
Main Authors: Pilipenko, Valentina V, He, Hua, Kurowski, Brad G, Alexander, Eileen S, Zhang, Xue, Ding, Lili, Mersha , Tesfaye B, Kottyan, Leah, Fardo, David W, Martin, Lisa J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144465/
https://ncbi.nlm.nih.gov/pubmed/25519373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S21
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